Most toddlers born with otoferlin deafness get cochlear implants in infancy and therefore are hence ineligible for your trial. The implants somewhat change the cochlea, which could hamper the interpretation of gene therapy final results.
“There has not been a Organic or health care or surgical technique to appropriate the underlying biological alterations that induce the internal ear not to perform,” Dr. Chan mentioned.
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The gene therapy is made of a harmless virus carrying new otoferlin genes in two drops of liquid that are delicately injected down the size of your cochlea, delivering the genes to every hair cell.
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